CovidSeniorV1, Main, Exploration, bibRecord, 000505

Impact of Vitamin D Deficiency on COVID-19-A Prospective Analysis from the CovILD Registry.

Identifieur interne : 000505 ( Main/Exploration ); précédent : 000504; suivant : 000506

Impact of Vitamin D Deficiency on COVID-19-A Prospective Analysis from the CovILD Registry.

Auteurs : Alex Pizzini [Autriche] ; Magdalena Aichner [Autriche] ; Sabina Sahanic [Autriche] ; Anna Böhm [Autriche] ; Alexander Egger [Autriche] ; Gregor Hoermann [Autriche, Allemagne] ; Katharina Kurz [Autriche] ; Gerlig Widmann [Autriche] ; Rosa Bellmann-Weiler [Autriche] ; Günter Weiss [Autriche] ; Ivan Tancevski [Autriche] ; Thomas Sonnweber [Autriche] ; Judith Löffler-Ragg [Autriche]

Source :

Nutrients [ 2072-6643 ] ; 2020.

RBID : pubmed:32932831

Descripteurs français

KwdFr :
- Adulte d'âge moyen (MeSH), Betacoronavirus (MeSH), Carence en vitamine D (sang), Carence en vitamine D (virologie), Carence en vitamine D (épidémiologie), Enregistrements (MeSH), Facteurs de risque (MeSH), Femelle (MeSH), Hormone parathyroïdienne (sang), Humains (MeSH), Indice de gravité de la maladie (MeSH), Infections à coronavirus (complications), Infections à coronavirus (sang), Infections à coronavirus (virologie), Mâle (MeSH), Pandémies (MeSH), Pneumopathie virale (complications), Pneumopathie virale (sang), Pneumopathie virale (virologie), Sujet âgé (MeSH), Vitamine D (analogues et dérivés), Vitamine D (sang), État nutritionnel (MeSH), Études prospectives (MeSH).
MESH :
- analogues et dérivés : Vitamine D.
- sang : Carence en vitamine D, Hormone parathyroïdienne, Infections à coronavirus, Pneumopathie virale, Vitamine D.
- virologie : Carence en vitamine D, Infections à coronavirus, Pneumopathie virale.
- épidémiologie : Carence en vitamine D.
- Adulte d'âge moyen, Betacoronavirus, Enregistrements, Facteurs de risque, Femelle, Humains, Indice de gravité de la maladie, Mâle, Pandémies, Sujet âgé, État nutritionnel, Études prospectives.

English descriptors

KwdEn :
- Aged (MeSH), Betacoronavirus (MeSH), Coronavirus Infections (blood), Coronavirus Infections (complications), Coronavirus Infections (virology), Female (MeSH), Humans (MeSH), Male (MeSH), Middle Aged (MeSH), Nutritional Status (MeSH), Pandemics (MeSH), Parathyroid Hormone (blood), Pneumonia, Viral (blood), Pneumonia, Viral (complications), Pneumonia, Viral (virology), Prospective Studies (MeSH), Registries (MeSH), Risk Factors (MeSH), Severity of Illness Index (MeSH), Vitamin D (analogs & derivatives), Vitamin D (blood), Vitamin D Deficiency (blood), Vitamin D Deficiency (epidemiology), Vitamin D Deficiency (virology).
MESH :
- chemical , analogs & derivatives : Vitamin D.
- chemical , blood : Parathyroid Hormone, Vitamin D.
- blood : Coronavirus Infections, Pneumonia, Viral, Vitamin D Deficiency.
- complications : Coronavirus Infections, Pneumonia, Viral.
- epidemiology : Vitamin D Deficiency.
- virology : Coronavirus Infections, Pneumonia, Viral, Vitamin D Deficiency.
- Aged, Betacoronavirus, Female, Humans, Male, Middle Aged, Nutritional Status, Pandemics, Prospective Studies, Registries, Risk Factors, Severity of Illness Index.

Abstract

The novel Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is a global health concern. Vitamin D (VITD) deficiency has been suggested to alter SARS-CoV-2 susceptibility and the course of disease. Thus, we aimed to investigate associations of VITD status to disease presentation within the CovILD registry. This prospective, multicenter, observational study on long-term sequelae includes patients with COVID-19 after hospitalization or outpatients with persistent symptoms. Eight weeks after PCR confirmed diagnosis, a detailed questionnaire, a clinical examination, and laboratory testing, including VITD status, were evaluated. Furthermore, available laboratory specimens close to hospital admission were used to retrospectively analyze 25-hydroxyvitamin D levels at disease onset. A total of 109 patients were included in the analysis (60% males, 40% females), aged 58 ± 14 years. Eight weeks after the onset of COVID-19, a high proportion of patients presented with impaired VITD metabolism and elevated parathyroid hormone (PTH) levels. PTH concentrations were increased in patients who needed intensive care unit (ICU) treatment, while VITD levels were not significantly different between disease severity groups. Low VITD levels at disease onset or at eight-week follow-up were not related to persistent symptom burden, lung function impairment, ongoing inflammation, or more severe CT abnormalities. VITD deficiency is frequent among COVID-19 patients but not associated with disease outcomes. However, individuals with severe disease display a disturbed parathyroid-vitamin-D axis within their recovery phase. The proposed significance of VITD supplementation in the clinical management of COVID-19 remains elusive.

DOI: 10.3390/nu12092775
PubMed: 32932831

Affiliations:

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Le document en format XML

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<sourceDesc><biblStruct><analytic><title xml:lang="en">Impact of Vitamin D Deficiency on COVID-19-A Prospective Analysis from the CovILD Registry.</title>
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<wicri:regionArea>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck</wicri:regionArea>
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<author><name sortKey="Aichner, Magdalena" sort="Aichner, Magdalena" uniqKey="Aichner M" first="Magdalena" last="Aichner">Magdalena Aichner</name>
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<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck</wicri:regionArea>
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<wicri:regionArea>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck</wicri:regionArea>
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<author><name sortKey="Bohm, Anna" sort="Bohm, Anna" uniqKey="Bohm A" first="Anna" last="Böhm">Anna Böhm</name>
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<affiliation wicri:level="3"><nlm:affiliation>Department of Laboratory Medicine, Medical University of Vienna, 1090 Vienna, Austria.</nlm:affiliation>
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<author><name sortKey="Kurz, Katharina" sort="Kurz, Katharina" uniqKey="Kurz K" first="Katharina" last="Kurz">Katharina Kurz</name>
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<author><name sortKey="Widmann, Gerlig" sort="Widmann, Gerlig" uniqKey="Widmann G" first="Gerlig" last="Widmann">Gerlig Widmann</name>
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<author><name sortKey="Bellmann Weiler, Rosa" sort="Bellmann Weiler, Rosa" uniqKey="Bellmann Weiler R" first="Rosa" last="Bellmann-Weiler">Rosa Bellmann-Weiler</name>
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<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck</wicri:regionArea>
<orgName type="university">Université de médecine d'Innsbruck</orgName>
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<author><name sortKey="Weiss, Gunter" sort="Weiss, Gunter" uniqKey="Weiss G" first="Günter" last="Weiss">Günter Weiss</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck</wicri:regionArea>
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</affiliation>
<affiliation wicri:level="4"><nlm:affiliation>Christian Doppler Laboratory for Iron Metabolism and Anemia Research, Medical University of Innsbruck, 6020 Innsbruck, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Christian Doppler Laboratory for Iron Metabolism and Anemia Research, Medical University of Innsbruck, 6020 Innsbruck</wicri:regionArea>
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</placeName>
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<author><name sortKey="Tancevski, Ivan" sort="Tancevski, Ivan" uniqKey="Tancevski I" first="Ivan" last="Tancevski">Ivan Tancevski</name>
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<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck</wicri:regionArea>
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<placeName><settlement type="city">Innsbruck</settlement>
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</placeName>
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<author><name sortKey="Sonnweber, Thomas" sort="Sonnweber, Thomas" uniqKey="Sonnweber T" first="Thomas" last="Sonnweber">Thomas Sonnweber</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck</wicri:regionArea>
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<placeName><settlement type="city">Innsbruck</settlement>
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</placeName>
</affiliation>
</author>
<author><name sortKey="Loffler Ragg, Judith" sort="Loffler Ragg, Judith" uniqKey="Loffler Ragg J" first="Judith" last="Löffler-Ragg">Judith Löffler-Ragg</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.</nlm:affiliation>
<country xml:lang="fr">Autriche</country>
<wicri:regionArea>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck</wicri:regionArea>
<orgName type="university">Université de médecine d'Innsbruck</orgName>
<placeName><settlement type="city">Innsbruck</settlement>
<region nuts="2" type="region">Tyrol (Land)</region>
</placeName>
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</analytic>
<series><title level="j">Nutrients</title>
<idno type="eISSN">2072-6643</idno>
<imprint><date when="2020" type="published">2020</date>
</imprint>
</series>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term>
<term>Betacoronavirus (MeSH)</term>
<term>Coronavirus Infections (blood)</term>
<term>Coronavirus Infections (complications)</term>
<term>Coronavirus Infections (virology)</term>
<term>Female (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Nutritional Status (MeSH)</term>
<term>Pandemics (MeSH)</term>
<term>Parathyroid Hormone (blood)</term>
<term>Pneumonia, Viral (blood)</term>
<term>Pneumonia, Viral (complications)</term>
<term>Pneumonia, Viral (virology)</term>
<term>Prospective Studies (MeSH)</term>
<term>Registries (MeSH)</term>
<term>Risk Factors (MeSH)</term>
<term>Severity of Illness Index (MeSH)</term>
<term>Vitamin D (analogs & derivatives)</term>
<term>Vitamin D (blood)</term>
<term>Vitamin D Deficiency (blood)</term>
<term>Vitamin D Deficiency (epidemiology)</term>
<term>Vitamin D Deficiency (virology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen (MeSH)</term>
<term>Betacoronavirus (MeSH)</term>
<term>Carence en vitamine D (sang)</term>
<term>Carence en vitamine D (virologie)</term>
<term>Carence en vitamine D (épidémiologie)</term>
<term>Enregistrements (MeSH)</term>
<term>Facteurs de risque (MeSH)</term>
<term>Femelle (MeSH)</term>
<term>Hormone parathyroïdienne (sang)</term>
<term>Humains (MeSH)</term>
<term>Indice de gravité de la maladie (MeSH)</term>
<term>Infections à coronavirus (complications)</term>
<term>Infections à coronavirus (sang)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Mâle (MeSH)</term>
<term>Pandémies (MeSH)</term>
<term>Pneumopathie virale (complications)</term>
<term>Pneumopathie virale (sang)</term>
<term>Pneumopathie virale (virologie)</term>
<term>Sujet âgé (MeSH)</term>
<term>Vitamine D (analogues et dérivés)</term>
<term>Vitamine D (sang)</term>
<term>État nutritionnel (MeSH)</term>
<term>Études prospectives (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Vitamin D</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Parathyroid Hormone</term>
<term>Vitamin D</term>
</keywords>
<keywords scheme="MESH" qualifier="analogues et dérivés" xml:lang="fr"><term>Vitamine D</term>
</keywords>
<keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
<term>Vitamin D Deficiency</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Vitamin D Deficiency</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Carence en vitamine D</term>
<term>Hormone parathyroïdienne</term>
<term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
<term>Vitamine D</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Carence en vitamine D</term>
<term>Infections à coronavirus</term>
<term>Pneumopathie virale</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia, Viral</term>
<term>Vitamin D Deficiency</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Carence en vitamine D</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Betacoronavirus</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Nutritional Status</term>
<term>Pandemics</term>
<term>Prospective Studies</term>
<term>Registries</term>
<term>Risk Factors</term>
<term>Severity of Illness Index</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term>
<term>Betacoronavirus</term>
<term>Enregistrements</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Humains</term>
<term>Indice de gravité de la maladie</term>
<term>Mâle</term>
<term>Pandémies</term>
<term>Sujet âgé</term>
<term>État nutritionnel</term>
<term>Études prospectives</term>
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<front><div type="abstract" xml:lang="en">The novel Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is a global health concern. Vitamin D (VITD) deficiency has been suggested to alter SARS-CoV-2 susceptibility and the course of disease. Thus, we aimed to investigate associations of VITD status to disease presentation within the CovILD registry. This prospective, multicenter, observational study on long-term sequelae includes patients with COVID-19 after hospitalization or outpatients with persistent symptoms. Eight weeks after PCR confirmed diagnosis, a detailed questionnaire, a clinical examination, and laboratory testing, including VITD status, were evaluated. Furthermore, available laboratory specimens close to hospital admission were used to retrospectively analyze 25-hydroxyvitamin D levels at disease onset. A total of 109 patients were included in the analysis (60% males, 40% females), aged 58 ± 14 years. Eight weeks after the onset of COVID-19, a high proportion of patients presented with impaired VITD metabolism and elevated parathyroid hormone (PTH) levels. PTH concentrations were increased in patients who needed intensive care unit (ICU) treatment, while VITD levels were not significantly different between disease severity groups. Low VITD levels at disease onset or at eight-week follow-up were not related to persistent symptom burden, lung function impairment, ongoing inflammation, or more severe CT abnormalities. VITD deficiency is frequent among COVID-19 patients but not associated with disease outcomes. However, individuals with severe disease display a disturbed parathyroid-vitamin-D axis within their recovery phase. The proposed significance of VITD supplementation in the clinical management of COVID-19 remains elusive.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32932831</PMID>
<DateCompleted><Year>2020</Year>
<Month>09</Month>
<Day>24</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>09</Month>
<Day>24</Day>
</DateRevised>
<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">2072-6643</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>12</Volume>
<Issue>9</Issue>
<PubDate><Year>2020</Year>
<Month>Sep</Month>
<Day>11</Day>
</PubDate>
</JournalIssue>
<Title>Nutrients</Title>
<ISOAbbreviation>Nutrients</ISOAbbreviation>
</Journal>
<ArticleTitle>Impact of Vitamin D Deficiency on COVID-19-A Prospective Analysis from the CovILD Registry.</ArticleTitle>
<ELocationID EIdType="pii" ValidYN="Y">E2775</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.3390/nu12092775</ELocationID>
<Abstract><AbstractText>The novel Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) is a global health concern. Vitamin D (VITD) deficiency has been suggested to alter SARS-CoV-2 susceptibility and the course of disease. Thus, we aimed to investigate associations of VITD status to disease presentation within the CovILD registry. This prospective, multicenter, observational study on long-term sequelae includes patients with COVID-19 after hospitalization or outpatients with persistent symptoms. Eight weeks after PCR confirmed diagnosis, a detailed questionnaire, a clinical examination, and laboratory testing, including VITD status, were evaluated. Furthermore, available laboratory specimens close to hospital admission were used to retrospectively analyze 25-hydroxyvitamin D levels at disease onset. A total of 109 patients were included in the analysis (60% males, 40% females), aged 58 ± 14 years. Eight weeks after the onset of COVID-19, a high proportion of patients presented with impaired VITD metabolism and elevated parathyroid hormone (PTH) levels. PTH concentrations were increased in patients who needed intensive care unit (ICU) treatment, while VITD levels were not significantly different between disease severity groups. Low VITD levels at disease onset or at eight-week follow-up were not related to persistent symptom burden, lung function impairment, ongoing inflammation, or more severe CT abnormalities. VITD deficiency is frequent among COVID-19 patients but not associated with disease outcomes. However, individuals with severe disease display a disturbed parathyroid-vitamin-D axis within their recovery phase. The proposed significance of VITD supplementation in the clinical management of COVID-19 remains elusive.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Pizzini</LastName>
<ForeName>Alex</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Aichner</LastName>
<ForeName>Magdalena</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sahanic</LastName>
<ForeName>Sabina</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Böhm</LastName>
<ForeName>Anna</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Egger</LastName>
<ForeName>Alexander</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Central Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Innsbruck, 6020 Innsbruck, Austria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hoermann</LastName>
<ForeName>Gregor</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Central Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Innsbruck, 6020 Innsbruck, Austria.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Laboratory Medicine, Medical University of Vienna, 1090 Vienna, Austria.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>MLL Munich Leukemia Laboratory, Klinikum Großhadern, 81377 Munich, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kurz</LastName>
<ForeName>Katharina</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Widmann</LastName>
<ForeName>Gerlig</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Department of Radiology, Medical University of Innsbruck, 6020 Innsbruck, Austria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bellmann-Weiler</LastName>
<ForeName>Rosa</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Weiss</LastName>
<ForeName>Günter</ForeName>
<Initials>G</Initials>
<Identifier Source="ORCID">0000-0003-0709-2158</Identifier>
<AffiliationInfo><Affiliation>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Christian Doppler Laboratory for Iron Metabolism and Anemia Research, Medical University of Innsbruck, 6020 Innsbruck, Austria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tancevski</LastName>
<ForeName>Ivan</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Sonnweber</LastName>
<ForeName>Thomas</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Löffler-Ragg</LastName>
<ForeName>Judith</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Department of Internal Medicine II, Infectious Diseases, Pneumology, Rheumatology, Medical University of Innsbruck, 6020 Innsbruck, Austria.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
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<PublicationType UI="D016448">Multicenter Study</PublicationType>
<PublicationType UI="D064888">Observational Study</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2020</Year>
<Month>09</Month>
<Day>11</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Switzerland</Country>
<MedlineTA>Nutrients</MedlineTA>
<NlmUniqueID>101521595</NlmUniqueID>
<ISSNLinking>2072-6643</ISSNLinking>
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<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D010281">Parathyroid Hormone</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>1406-16-2</RegistryNumber>
<NameOfSubstance UI="D014807">Vitamin D</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>A288AR3C9H</RegistryNumber>
<NameOfSubstance UI="C104450">25-hydroxyvitamin D</NameOfSubstance>
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<SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName>
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</MeshHeading>
<MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="Y">Betacoronavirus</DescriptorName>
</MeshHeading>
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<QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009752" MajorTopicYN="N">Nutritional Status</DescriptorName>
</MeshHeading>
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</MeshHeading>
<MeshHeading><DescriptorName UI="D010281" MajorTopicYN="N">Parathyroid Hormone</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012042" MajorTopicYN="N">Registries</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012720" MajorTopicYN="N">Severity of Illness Index</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014807" MajorTopicYN="N">Vitamin D</DescriptorName>
<QualifierName UI="Q000031" MajorTopicYN="Y">analogs & derivatives</QualifierName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014808" MajorTopicYN="N">Vitamin D Deficiency</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">COVID-19</Keyword>
<Keyword MajorTopicYN="N">PTH</Keyword>
<Keyword MajorTopicYN="N">SARS-CoV-2</Keyword>
<Keyword MajorTopicYN="N">VITD</Keyword>
<Keyword MajorTopicYN="N">parathyroid hormone</Keyword>
<Keyword MajorTopicYN="N">vitamin D</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year>
<Month>08</Month>
<Day>10</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2020</Year>
<Month>09</Month>
<Day>07</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2020</Year>
<Month>09</Month>
<Day>09</Day>
</PubMedPubDate>
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<Month>9</Month>
<Day>16</Day>
<Hour>1</Hour>
<Minute>1</Minute>
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<Day>17</Day>
<Hour>6</Hour>
<Minute>0</Minute>
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<Day>25</Day>
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<li>Autriche</li>
</country>
<region><li>Bavière</li>
<li>District de Haute-Bavière</li>
<li>Tyrol (Land)</li>
<li>Vienne (Autriche)</li>
</region>
<settlement><li>Innsbruck</li>
<li>Munich</li>
<li>Vienne (Autriche)</li>
</settlement>
<orgName><li>Université de médecine d'Innsbruck</li>
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<tree><country name="Autriche"><region name="Tyrol (Land)"><name sortKey="Pizzini, Alex" sort="Pizzini, Alex" uniqKey="Pizzini A" first="Alex" last="Pizzini">Alex Pizzini</name>
</region>
<name sortKey="Aichner, Magdalena" sort="Aichner, Magdalena" uniqKey="Aichner M" first="Magdalena" last="Aichner">Magdalena Aichner</name>
<name sortKey="Bellmann Weiler, Rosa" sort="Bellmann Weiler, Rosa" uniqKey="Bellmann Weiler R" first="Rosa" last="Bellmann-Weiler">Rosa Bellmann-Weiler</name>
<name sortKey="Bohm, Anna" sort="Bohm, Anna" uniqKey="Bohm A" first="Anna" last="Böhm">Anna Böhm</name>
<name sortKey="Egger, Alexander" sort="Egger, Alexander" uniqKey="Egger A" first="Alexander" last="Egger">Alexander Egger</name>
<name sortKey="Hoermann, Gregor" sort="Hoermann, Gregor" uniqKey="Hoermann G" first="Gregor" last="Hoermann">Gregor Hoermann</name>
<name sortKey="Hoermann, Gregor" sort="Hoermann, Gregor" uniqKey="Hoermann G" first="Gregor" last="Hoermann">Gregor Hoermann</name>
<name sortKey="Kurz, Katharina" sort="Kurz, Katharina" uniqKey="Kurz K" first="Katharina" last="Kurz">Katharina Kurz</name>
<name sortKey="Loffler Ragg, Judith" sort="Loffler Ragg, Judith" uniqKey="Loffler Ragg J" first="Judith" last="Löffler-Ragg">Judith Löffler-Ragg</name>
<name sortKey="Sahanic, Sabina" sort="Sahanic, Sabina" uniqKey="Sahanic S" first="Sabina" last="Sahanic">Sabina Sahanic</name>
<name sortKey="Sonnweber, Thomas" sort="Sonnweber, Thomas" uniqKey="Sonnweber T" first="Thomas" last="Sonnweber">Thomas Sonnweber</name>
<name sortKey="Tancevski, Ivan" sort="Tancevski, Ivan" uniqKey="Tancevski I" first="Ivan" last="Tancevski">Ivan Tancevski</name>
<name sortKey="Weiss, Gunter" sort="Weiss, Gunter" uniqKey="Weiss G" first="Günter" last="Weiss">Günter Weiss</name>
<name sortKey="Weiss, Gunter" sort="Weiss, Gunter" uniqKey="Weiss G" first="Günter" last="Weiss">Günter Weiss</name>
<name sortKey="Widmann, Gerlig" sort="Widmann, Gerlig" uniqKey="Widmann G" first="Gerlig" last="Widmann">Gerlig Widmann</name>
</country>
<country name="Allemagne"><region name="Bavière"><name sortKey="Hoermann, Gregor" sort="Hoermann, Gregor" uniqKey="Hoermann G" first="Gregor" last="Hoermann">Gregor Hoermann</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/CovidSeniorV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000505 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000505 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    CovidSeniorV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:32932831
   |texte=   Impact of Vitamin D Deficiency on COVID-19-A Prospective Analysis from the CovILD Registry.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:32932831" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a CovidSeniorV1

This area was generated with Dilib version V0.6.37.
Data generation: Thu Oct 15 09:49:45 2020. Site generation: Wed Jan 27 17:10:23 2021

	Serveur d'exploration sur la COVID chez les séniors
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur la COVID chez les séniors

Impact of Vitamin D Deficiency on COVID-19-A Prospective Analysis from the CovILD Registry.

Impact of Vitamin D Deficiency on COVID-19-A Prospective Analysis from the CovILD Registry.

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